The body, its diseases, the medicine, and the institutions around them.
The conditions themselves — what is known, what is being researched, and what remains uncertain.
Showing this group ·The arguments medicine keeps having with itself — cholesterol, biologics, and the system that resists correction.
Open this group →The practical interventions with actual evidence — diet, sleep, movement, and the slow reconstruction of function.
Browse this topic →Myasthenia gravis is caused by antibodies that block acetylcholine receptors at the neuromuscular junction. The nerve fires normally, but t…
Vitiligo is the selective destruction of melanocytes — the cells that produce skin pigment — by cytotoxic CD8+ T-cells that recognise melan…
Ankylosing spondylitis targets the sacroiliac joints and spine with a unique perversity: instead of merely destroying joints, it replaces t…
Sjögren's syndrome targets the exocrine glands — particularly the salivary and lacrimal glands — with lymphocytic infiltration that destroy…
Celiac disease is the one autoimmune condition with a completely identified dietary trigger: gliadin, the alcohol-soluble fraction of wheat…
Psoriasis is driven by IL-17 and IL-23 cytokines that lock the skin into a state of hyperproliferation. Keratinocytes that normally renew o…
Graves' disease is the mirror image of Hashimoto's: instead of destroying the thyroid, the immune system produces antibodies that mimic TSH…
Hashimoto's thyroiditis is the most common cause of hypothyroidism in the developed world. Lymphocytes infiltrate the thyroid gland, destro…
Type 1 diabetes is not a failure of the pancreas — it is an immune attack on the pancreas. Autoreactive T-cells destroy the beta cells of t…
Ulcerative colitis confines its destruction to the inner lining of the large intestine, but the sustained mucosal inflammation produces con…
Crohn's disease is a transmural inflammation — it burns through the full thickness of the intestinal wall. Unlike ulcerative colitis which …
Rheumatoid arthritis is driven by immune cells that invade the synovial lining of joints, forming an aggressive pannus tissue that erodes c…
In multiple sclerosis, autoreactive T-cells cross the blood-brain barrier and destroy myelin — the insulating sheath around nerve fibres. W…
In lupus, the immune system produces antibodies against the body's own DNA. Those antibodies form immune complexes that lodge in the kidney…
How insulin unlocks glucose uptake in healthy cells, why cells stop responding in Type 2 diabetes, what happens when insulin is injected to…
Dr. Zsófia Clemens has shown that autoimmune disease begins not in the immune system — but in the gut. When the wrong foods damage your gut…
Psoriasis is an autoimmune condition in which the immune system attacks the skin, producing plaques, scales, and inflamed patches that can …
Rheumatoid arthritis has long been considered a progressive, irreversible disease—one in which the immune system attacks joint linings, cau…
Crohn's disease, an inflammatory bowel condition that can strike anywhere from mouth to anus, has long been treated with immune-suppressing…
Ulcerative colitis, an inflammatory bowel disease characterized by ulcers and chronic inflammation in the large intestine, typically consig…
Hashimoto's thyroiditis, the leading cause of hypothyroidism in the Western world, begins when the immune system turns against the thyroid …
Lupus—systemic lupus erythematosus—attacks joints, skin, kidneys, and brain with an immune system that has turned against the body. The sta…
Multiple sclerosis destroys the fatty myelin sheath that insulates nerve fibers, leaving patients with vision loss, tremors, fatigue, and p…
Chronic fatigue syndrome and myalgic encephalomyelitis remain among the most poorly understood conditions in modern medicine, often leaving…
Fibromyalgia — a constellation of widespread pain, crushing fatigue, and cognitive fog — has long frustrated both patients and clinicians. …
Celiac disease — the autoimmune condition triggered by gluten that flattens the villi of the small intestine — has a known dietary fix: eli…
Type 1 diabetes is an autoimmune disease in which the immune system destroys the insulin-producing beta cells of the pancreas, leaving pati…
Polycystic ovary syndrome affects somewhere between five and ten percent of women of reproductive age and stands as the most common cause o…
Endometriosis—a condition in which tissue resembling the uterine lining grows outside the uterus, causing chronic pain, heavy bleeding, and…
Graves' disease attacks the thyroid gland, forcing it to flood the body with excess hormone—a state called hyperthyroidism that sends the h…